Development of the Arabic version of Reflux Symptom Index.

BACKGROUND AND OBJECTIVE: Reflux Symptom Index (RSI), is a nine-item self-administered questionnaire. It is a noninvasive tool with the purpose of assessing the symptoms of laryngopharyngeal reflux (LPR). The purposes of the present study were to develop an Arabic version of the RSI and to evaluate its validity, consistency, and reliability in normal Arabic population with suspected LPR. SETTING AND DESIGN: This is a prospective study that has been carried out at Communication and Swallowing Disorders Unit, King Saud University, Riyadh, Saudi Arabia. SUBJECTS AND METHODS: The generated Arabic RSI was administered to 52 patients with suspected LPR and to 100 control subjects. Internal consistency and test-retest reliability were evaluated. The results of the patients and the control groups were compared. RESULTS: The Arabic RSI showed satisfactory internal consistency (Cronbach's α=.72). Also, good test-retest reliability was found for the total scores of the Arabic RSI (r=0.9799, P=0.001). There was a significant difference between RSI scores of the control and the LPR group (P<0.001). CONCLUSION: This study demonstrated that Arabic RSI is a valid tool for self-assessment of LPR that can be used by Arabic language speakers.

Prevalence of gastroesophageal reflux symptoms in adolescents: is there a difference in different racial and ethnic groups?

The study aims to determine if differences exist among racial/ethnic groups in the prevalence of gastroesophageal reflux symptoms in adolescents. A cross-sectional questionnaire was administered to a sample of students in four racially and ethnically diverse high schools in suburban Chicago. A total of 2561 questionnaires were analyzed: 33% Hispanics, 30% Caucasians, 22% African Americans, 15% Asians, 54% female, mean age 15.8 (±1.3) years. Thirty-two percent had at least one esophageal and/or respiratory symptom ≥once a week. Caucasians and African Americans had more dysphagia than Hispanics and Asians (7% vs. 4%; P= 0.04). Hispanics had more heartburn (13% vs. 9-11%; P= 0.06) but this was not statistically significant. There was no difference for regurgitation. Hispanic females had more dysphagia (6% vs. 3%; P= 0.02) and heartburn (17% vs. 9%; P= 0.0003) than Hispanic males. African Americans and Caucasians had more respiratory symptoms than Hispanics and Asians (29%, 24% vs. 18%; P= 0.000004). Students with esophageal symptoms were more likely to have respiratory symptoms (46% vs. 17%; P < 0.0005). African Americans and Caucasians with esophageal symptoms had more respiratory symptoms than Hispanics and Asians with esophageal symptoms (55%, 49% vs. 42%, 34%; P= 0.0003). Asians and Hispanics were less likely to treat symptoms than African Americans and Caucasians (26%, 33% vs. 47%, 49%; P= 0.001). We found that differences exist among the racial/ethnic groups with esophageal and respiratory symptoms; esophageal symptoms are a risk factor for respiratory symptoms, and Asians and Hispanics seek less medical help. Future research should focus on whether the differences found continue and reasons for them.

Ambulatory 24-hour pharyngeal pH monitoring in healthy Korean volunteers.

Pharyngeal pH monitoring is the standard diagnostic approach for laryngopharyngeal reflux (LPR). However, the normal values for Asian populations are still unknown. We evaluated the results of ambulatory 24-h pharyngeal pH monitoring in healthy volunteers to determine the normal reference values in the Korean population. Thirty healthy subjects underwent ambulatory 24-h pharyngeal pH monitoring with glass electrodes positioned 1 cm above the upper esophageal sphincter and 5 cm above the lower esophageal sphincter, based on esophageal manometry after upper gastrointestinal endoscopy. LPR occurred in about one half of the healthy volunteers without any significant association with age, gender and body mass index. Pharyngeal acid reflux occurred mainly in the upright position. At the 95th and 90th percentile, after the exclusion of mealtimes, the upper limits of normal (ULN) for pharyngeal acid exposure were 0.41% and 0.18%. The ULNs for the number of pharyngeal acid events were 12.8 and 5.0. The corresponding ULNs for the esophagus were 5.1% and 3.8% and 62.7 and 32.6. The findings of this study help establish the reference standards for LPR in Korean patients.